In the pharmaceutical factory, the central air conditioning purification system completes the purification and disinfection of each clean area. The method is to put the ozone generator directly in the air duct of the air conditioning purification system, which is called a built-in ozone generator. The ozone is sent into each clean area along with the air flow of the air duct, and the clean area is disinfected and sterilized. The remaining ozone is sucked into the air return port and taken away by the central air conditioner. The ozone generator can also be placed outside the air outlet of the central air conditioner, and the ozone can be injected into the air duct of the central air conditioner, and then sent to each clean room, which is called an external ozone generator.

The external ozone generator is easy to install and maintain, but the manufacturing cost is higher. The disinfection effect of the two methods is the same. According to the requirements of the Ministry of Health's disinfection technical specifications, the ozone concentration for air disinfection is 5ppm, but in fact, the disinfection of the clean area is not only the disinfection of the air, but also the disinfection of the surface of the object. Therefore, the concentration is designed Generally, it should be greater than 10ppm. It can be turned on for 1-2 hours before get off work and 1 hour after work every day to ensure that the planktonic bacteria and sedimentation bacteria in the clean area meet the requirements of GMP within a day.

Disinfection and sterilization of space

For clean rooms other than the central air-conditioning purification system, or other rooms that need to be sterilized, they need to be sterilized separately. The method is to select an ozone generator and install it directly in the room. Set the disinfection time as needed, and it will automatically shut down after disinfection, so it is very convenient to use. Select and use according to the size of the room space. As long as the requirements of ozone concentration are met, the purpose of disinfection and sterilization can be achieved. It is much easier than using chemical reagents to fumigate the room. It can completely replace chemical fumigation, shorten the disinfection time and avoid secondary pollution.

Surface disinfection and sterilization of items

In the process of pharmaceutical production, it is often necessary to disinfect the surface of raw materials, tools and equipment, packaging, and production sites. The traditional method is to use ultraviolet rays to disinfect, but the disinfection is not thorough, there are dead spots, fast attenuation, and inability to kill certain bacteria in a specific environment. The "Disinfection Technical Specification" introduced that for the surface of an object immersed in ozone gas, contact for a period of time can kill the surface bacteria.